Hyaluronic acid preparation to be used for treating inflammations of skeletal joints

Patent 4801619 Issued on January 31, 1989. Estimated Expiration Date:

November 4, 2006. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

3396081

Ultrapure hyaluronic acid and the use thereof
Patent #: 4141973
Issued on: 02/27/1979
Inventor: Balazs

Ophthalmological procedures
Patent #: 4328803
Issued on: 05/11/1982
Inventor: Pape

Hyaluronic acid from bacterial culture Patent #: 4517295
Issued on: 05/14/1985
Inventor: Bracke , et al.

Inventor

Lindblad, Gert T.

Assignee

Pharmacia AB

Application

No. 06/934410 filed on 11/04/1986

US Classes:

514/42, N-glycoside514/54, Polysaccharide536/55.1Polysaccharides

Examiners

Primary: Griffin, Ronald W.

Attorney, Agent or Firm

Philpitt; Fred

International Classes

C08B 37/00 (20060101)
C08B 37/08 (20060101)

Foreign Application Priority Data

1985-04-09 SE

Abstract

Hyaluronic acid preparation containing an effective amount of hyaluronic acid of a molecular weight exceeding 3×106 dalton, for intra-articular administration in the treatment of steroid arthropathy and progressive cartilage degeneration caused by proteoglycan degradation.

Other References

Research in Veterinary Science, vol. 30, No. 2, issued 1981 (Oxford), D. A. Gingerich et al., "Effect of Exogenous Hyaluronic Acid on Joint Function in Experimentally Induced Equine Osteoarthritis: Dosage Titration Studies", see pp. 192-197, especially p. 192 and pp. 196-197 (Discussion)
International Journal of Clinical Pharmacology, Therapy and Toxicology, vol. 20, No. 11, issued 1982 (Munich), O. Namiki et al., "Therapeutic Effect of Intra-Articular Injection of High Molecular Weight Hyaluronic Acid on Osteoarthritis of the Knee", see pp. 501-507, especially p. 501 and pp. 504-506 (Discussion)
Patent Abstracts of Japan, vol. 7, No. 118, C-167, Abstract of JP 58-37001 (A), published 1983-03-04
Upsala, Journal of Medical Sciences, Supplement 17. issued 1975 (Uppsala), A. Wigren et al., "Repeated Intraarticular Implantation of Hyaluronic Acid", see pp. 1-20, especially p. 3 and p. 19 (Summary)
Proceedings of the Twenty-Fourth Annual Convention of the American Association of Equine Practitioners, St. Louis, Missouri, Dec. 2-6, 1978, published 1979 by American Association of Equine Practitioners, O. G. Swanstrom, "Hyaluronate (Hyaluronate Acid) and its Use", see pp. 345-348, especially p. 345, first two paragraphs, and p. 347, second paragraph