Processes for making colored pharmaceutical compositions
Patent 4801454 Issued on January 31, 1989. Estimated Expiration Date: 
July 17, 2006. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
July 17, 2006. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.InventorAssigneeApplicationNo. 06/887671 filed on 07/17/1986US Classes:424/653, Bismuth514/503Antimony or bismuthExaminersPrimary: Waddell, Frederick E.Attorney, Agent or FirmInternational ClassesA61K 33/24 (20060101)A61K 31/29 (20060101) A61K 31/28 (20060101) A61K 9/00 (20060101) AbstractProcesses for making colored pharmaceutical compositions, by the steps of:(a) preparing an aqueous mixture having a pH of at least about 5, containing a suspension agent, and a pharmaceutically-acceptable bismuth salt at a level of from about 0.5% to about 3%, by weight of final composition;(b) adding a quantity of FD&C Red 3 dye to the mixture;(c) mixing the mixture for at least about 30 seconds; and(d) adjusting the pH of the mixture to a pH in the range of from about 3.4 to about 4.Preferably, the bismuth salt is bismuth subsalicylate. Preferred suspension agents include mixtures of magnesium aluminum silicate and methyl cellulose and of magnesium aluminum silicate and xanthan gum.Other References
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