U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Orally administerable sustained release pharmaceutical formulations

Patent 4797286 Issued on January 10, 1989. Estimated Expiration Date: Icon_subject January 10, 2006. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Method of forming truss plates Patent #: 4625535
Issued on: 12/02/1986
Inventor: Birckhead

Inventors

Assignee

Application

No. 06/797305 filed on 11/12/1985

US Classes:

424/456, Gelatin424/457Sustained or differential release

Examiners

Primary: Page, Thurman K.
Assistant: Horne, Leon R.

Attorney, Agent or Firm

International Class

A61K 9/48 (20060101)

Abstract

This invention provides orally administerable pharmaceutical formulations having a semi-solid matrix containing a hydrophilic substance capable of creating channels in a hydrophobic carrier matrix thereby providing a sustained rate of release of an active agent from the formulation.

Other References

  • Chemical Abstracts, vol. 89: 80177p "Effect of Hydrophilization of Hydrophobic on Release Rate from Capsules" Leck, C. F. et al J. Pharm. Sci. 1978, 67(7), 935-9
  • Chemical Abstracts vol. 91, 1979: 27262c, "In vitro and In Viro Availability of Hydrophilized Phenytoin from Capsules", Lerk, C. F. et al., J. Pharm. Soi. 1979, 68(5), 634-8
  • Hunter et al., Pharm. Ind. 45, 4, 433-434 (1983)
  • Product Bulletin, "The Hard Capsule with the Soft Centre", Elanco Products
  • Product Bulletin, "Gelucire.RTM., Gattefosse Corporation (1983)
  • Francois et al., Pharm. Ind., 44, 1, 86-89 (1982)
  • Hunter et al., Pharm. Ind., 44, 1, 90-91 (1982)
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