Process for the preparation of imidazopyridines
Patent 4794185 Issued on December 27, 1988. Estimated Expiration Date: 
June 26, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
June 26, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesImidazo[1,2-a] pyridine derivatives and their application as pharmaceuticals 6-Methyl-2-(4-methylthiophenyl)-i midazo[1,2-a]-pyridine-3-N,N-dimethylacetamide Patent #: 4460592 InventorsAssigneeApplicationNo. 07/066530 filed on 06/26/1987US Classes:546/121Ring nitrogen is shared by the two cyclosExaminersPrimary: Lee, Mary C.Assistant: Dentz, Bernard Attorney, Agent or FirmInternational ClassesC07D 471/00 (20060101)C07D 471/04 (20060101) Foreign Application Priority Data1986-06-27 FRAbstractA process for the preparation of an imidazopyridine which is a compound of formula (I) ##STR1## in which: Y denotes hydrogen, a halogen or a C1-4 alkyl group;X1 and X2 denote, independently of each other, hydrogen, a halogen or a C1-4 alkoxy, C1-6 alkyl, CF3, CH3 S, CH3 SO2 or NO2 group; andR1 and R2 denote, independently of each other, hydrogen or a C1-5 alkyl group, with the proviso that R1 and R2 do not both denote hydrogen,or a salt thereof;which process comprises reacting a compound of formula (V) ##STR2## wherein Y, X1, X2, R1 and R2 are as defined above, with a reducing agent and if desired converting the resulting compound of formula (I) into a salt, together with intermediates of formulae: ##STR3## The final products have useful pharmacological properties, e.g. as anxiolytics.Other References
Field of SearchRing nitrogen is shared by the two cyclos |
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