Process for producing bovine lactoferrin in high purity
Patent 4791193 Issued on December 13, 1988. Estimated Expiration Date: 
July 16, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
July 16, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3234199 Method of separating proteins by ion exchange Process for extracting proteins from milk using silica and anion exchange resins Cation-exchange of milk and products thereof Process of extraction of lactoferrine and immunoglobulins of milk Method for separating bovine lactoferrin from cow's milk and purifying same Patent #: 4668771 InventorsAssigneeApplicationNo. 07/074034 filed on 07/16/1987US Classes:530/416, Ion exchange426/657, From animal530/365, Lactalbumin, e.g., milk source, etc.530/366, Separation, purification or synthesis530/832, Milk; colostrum530/833Whey; cheeseExaminersPrimary: Schain, Howard E.Attorney, Agent or FirmInternational ClassesA23J 1/00 (20060101)A23J 1/20 (20060101) Foreign Application Priority Data1986-07-17 JPAbstractA process for producing bovine lactoferrin in high purity form raw milk-materials containing skim milk or whey originated form cow's milk which comprises: adsoption step wherein said raw materials are contacted, at a temperature between 0°-60° C., with weakly acidic cation-exchanger which includes carboxymethyl groups as ion exchanging groups and has haemoglobin adsorption property more than 3.5 g/100 ml; rinsing step wherein said exchanger is washed with water to remove substances other than those adsorbed to said exchanger; and desorption step wherein the substances adsorbed to said exchanger are desorbed therefrom with a solution of one or more of salts to thereby yield highly purified bovine lactoferrin without deterirating raw milk materials. Said desorption step can be carried out in a single stage to produce lactoferrin more than 80% purity to total proteins recovered, and in two stage to attain more than 98% purity.Other References
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