External pharmaceutical composition and methods of use
Patent 4789667 Issued on December 6, 1988. Estimated Expiration Date: 
December 6, 2005. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
December 6, 2005. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.InventorsAssigneeApplicationNo. 06/771764 filed on 09/03/1985US Classes:514/161, With heterocyclic compound514/159, Ortho-hydroxybenzoic acid (i.e., salicyclic acid) or derivative DOAI514/177, Oxygen double bonded to a ring carbon of the cyclopentanohydrophenanthrene ring system514/420, Indomethacine per se or ester thereof514/946, PENETRANT OR ABSORBENT (ENHANCES PENETRATION INTO SUBJECT TREATED)514/947, Topical application514/969OINTMENT OR SALVE BASEExaminersPrimary: Friedman, Stanley J.Attorney, Agent or FirmInternational ClassA61K 47/22 (20060101)Foreign Application Priority Data1984-09-03 JPAbstractA pharmaceutical composition for external use with the enhanced penetration of a pharmacologically active agent through the skin or mucosa of a warm-blooded animal, said composition comprising(A) a pharmaceutically effective amount of the pharmacologically active agent, and(B) an optically active or inactive pyroglutamate of the following formula ##STR1## wherein R represents a linear, branched or cyclic alkyl or alkenyl group having 10 to 14 carbon atoms,as a penentration enhancer.Other References
Field of SearchOrtho-hydroxybenzoic acid (i.e., salicyclic acid) or derivative DOAIWith heterocyclic compound OINTMENT OR SALVE BASE PENETRANT OR ABSORBENT (ENHANCES PENETRATION INTO SUBJECT TREATED) Topical application Oxygen double bonded to a ring carbon of the cyclopentanohydrophenanthrene ring system Indomethacine per se or ester thereof | |
