Patent References 2990332 Prolonged release pharmaceutical preparations Thixotropic compositions easily convertible to pourable liquids Patent #: 4427681 InventorsAssigneeApplicationNo. 06/806879 filed on 12/09/1985US Classes:424/483, Ion-exchange resins424/78.14, Nitrogen heterocycle514/289, Two of the cyclos share at least three ring members (i.e., bridged) (e.g., morphinans, etc.)514/850AntitussiveExaminersPrimary: Schenkman, LeonardAttorney, Agent or FirmInternational ClassesA61K 47/48 (20060101)A61K 31/485 (20060101) AbstractA pharmaceutical preparation for controlled, sustained release of dextromethorphan comprising a polystyrene sulfonate resin which has been cross-linked with about 3% to about 10% divinyl benzene, having an average particle size of at least 48 μm and less than 100 μm onto which dextromethorphan has been loaded in a ratio of dextromethorphan hydrobromid to resin of about 1:3 to about 1:10 and at least one pharmaceutically acceptable adjuvant.Other References
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