Controlled release tablet

Patent 4784858 Issued on November 15, 1988. Estimated Expiration Date:

August 22, 2006. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

New oral form of medicament and a method for producing it
Patent #: 4083949
Issued on: 04/11/1978
Inventor: Benedikt

Prolonged-release pharmaceutical compositions for oral administration, their methods of making and use
Patent #: 4155993
Issued on: 05/22/1979
Inventor: Belleville , et al.

Sustained release pharmaceutical compositions
Patent #: 4248858
Issued on: 02/03/1981
Inventor: Guley , et al.

Controlled release tablet
Patent #: 4252786
Issued on: 02/24/1981
Inventor: Weiss , et al.

Method for preparing a pharmaceutical controlled release composition
Patent #: 4572833
Issued on: 02/25/1986
Inventor: Pedersen , et al.

Combination formulation
Patent #: 4574080
Issued on: 03/04/1986
Inventor: Roswall , et al.

Pharmaceutical multiple-units formulation
Patent #: 4606909
Issued on: 08/19/1986
Inventor: Bechgaard , et al.

Storage-stable, quick-disintegrating pressed shapes containing pharmaceutical active substances Patent #: 4666703
Issued on: 05/19/1987
Inventor: Kopf

Inventor

Ventouras, Kimon

Application

No. 06/899112 filed on 08/22/1986

US Classes:

424/468, Sustained or differential release type424/469, Discrete particles in supporting matrix424/470, Where particles are granulated424/473, With porous, perforated, apertured, or sieved layer (e.g., dialyzing layer, microporous layer, etc.)424/482, Containing solid synthetic polymers424/488Polysaccharides (e.g., cellulose, etc.)

Examiners

Primary: Rose, Shep K.

Attorney, Agent or Firm

Fishman; Irving M.

International Classes

A61K 9/20 (20060101)
A61K 9/28 (20060101)

Foreign Application Priority Data

1985-08-29 GB

Abstract

A controlled release tablet comprising(I) a core, containing as essential components(a) at least one water-soluble pharmaceutically active substance which is dispersed in a water-insoluble, non-digestible polymeric excipient, and(b) a water-insoluble polymeric substance, which is swellable under the influence of water, and(II) a coating essentially of an elastic, water-insoluble and semipermeable diffusion film of a polymer,is presented, which shows a release pattern for the active substance(s) in a programmed rate of approximately zero order.