U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Transdermal therapeutic composition

Patent 4781926 Issued on November 1, 1988. Estimated Expiration Date: Icon_subject March 21, 2006. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Polymeric diffusion matrix containing clonidine
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Polymeric diffusion matrix containing phenylephrine
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Polymeric diffusion matrix containing ester derivatives of estradiol
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Polymeric diffusion matrix containing propranolol
Patent #: 4482533
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Trinitroglycerol sustained release vehicles and preparation therefrom
Patent #: 4542013
Issued on: 09/17/1985
Inventor: Keith

Active agent containing hydrogel devices wherein the active agent concentration profile contains a sigmoidal concentration gradient for improved constant release, their manufacture and use
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Inventors

Assignee

Application

No. 06/842187 filed on 03/21/1986

US Classes:

424/486, Synthetic polymer424/485Natural gums, resin or latex

Examiners

Primary: Page, Thurman K.
Assistant: Horne, Leon R.

Attorney, Agent or Firm

International Classes

A61K 9/70 (20060101)
A61K 47/32 (20060101)

Foreign Application Priority Data

1985-03-25 JP

Abstract

Transdermal dosage compositions are prepared from hydrated poly(vinyl alcohol) gels and pharmacologically active substances without any chemicals such as crosslinking agents and catalysts. Heating process is not involved in the gel preparation. High water contents of the gels enable the stratum corneum to be swollen, resulting in high permeation of drugs through the skin.

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