Method of producing slow-release pharmaceutical forms

Patent 4780322 Issued on October 25, 1988. Estimated Expiration Date:

January 21, 2006. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

3108044

3138525

3594470

3608063

Universally useable tableting ingredients
Patent #: 4013820
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Patent #: 4499066
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Inventor: Moro , et al.

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Inventor: Bechgaard , et al.

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Microphase separated hydrogels for controlled release of bioactive materials Patent #: 4693887
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Inventor: Shah

Inventors

Application

No. 06/820151 filed on 01/21/1986

US Classes:

424/78.11, Plural ion exchange resins424/497, Containing solid synthetic polymers424/78.14, Nitrogen heterocycle514/282, One of the five cyclos is five-membered and includes ring chalcogen (e.g., codeine, morphine, etc.)514/289, Two of the cyclos share at least three ring members (i.e., bridged) (e.g., morphinans, etc.)514/619, Nitrogen in R514/944, GEL514/964, SUSTAINED OR DIFFERENTIAL RELEASE TYPE514/965, Discrete particles in supporting matrix525/191Polymer mixture of two or more solid polymers derived from ethylenically unsaturated reactants only; or mixtures of said polymer mixture with a chemical treating agent; or products or processes of preparing any of the above mixtures

Examiners

Primary: Griffin, Ronald W.

Attorney, Agent or Firm

Oblon, Fisher, Spivak, McClelland & Maier

International Classes

A61K 47/48 (20060101)
A61K 47/32 (20060101)

Foreign Application Priority Data

1985-01-21 FR

Abstract

The invention relates to a novel method of producing slow-release pharmaceutical forms administered per os, by simultaneously employing two resins having anionic character, the proportions of said resins being variable.By varying the ratio of the amounts of active principles on the respective two resins, it is possible to modify the release kinetics of active principle; and by independently varying the amount of carboxylic resin it is possible to produce stabile pharmaceutical preparations which are in liquid, semi-liquid, or solid form.