U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Controlled release drug delivery system for the periodontal pocket

Patent 4780320 Issued on October 25, 1988. Estimated Expiration Date: Icon_subject April 29, 2006. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3185625

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Issued on: 08/03/1976
Inventor: Tsuk ,   et al.

Long-acting articles for oral delivery and process
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Issued on: 08/02/1977
Inventor: DeFoney ,   et al.

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Inventor: Tanaka ,   et al.

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Issued on: 10/07/1980
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Method and preparation for administration to the mucosa of the oral or nasal cavity
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Inventor: Nagai ,   et al.

Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
Patent #: 4369172
Issued on: 01/18/1983
Inventor: Schor ,   et al.

Drug delivery system comprising a reservoir containing a plurality of tiny pills
Patent #: 4434153
Issued on: 02/28/1984
Inventor: Urquhart ,   et al.

Composition for periodontal administration
Patent #: 4568535
Issued on: 02/04/1986
Inventor: Loesche

Controlled release of pharmacologically active agents from an absorbable biologically compatible putty-like composition
Patent #: 4568536
Issued on: 02/04/1986
Inventor: Kronenthal ,   et al.

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Inventor

Assignee

Application

No. 06/856961 filed on 04/29/1986

US Classes:

424/493, Containing polysaccharides (e.g., sugars)424/486, Synthetic polymer424/497Containing solid synthetic polymers

Examiners

Primary: Swisher, Nancy A. B.

Attorney, Agent or Firm

International Classes

A61K 9/16 (20060101)
A61K 9/00 (20060101)
A61K 6/00 (20060101)

Abstract

A controlled release drug delivery system for placement in the periodontal pocket. The system comprises a plurality of drug-containing microparticles or microcapsules, between 10 and 500 microns in size, suspended in a pharmaceutically acceptable carrier medium, and is capable of maintaining an effective level of drug in the periodontal pocket for a period of 1 to 30 days.

Other References

  • J Slots, "Subgingival Microflora + Periodontal Disease," J. Clin. Periodontol, 6, 315 (1979)
  • S. S. Socranksky, "Microbiology of Periodontal Disease-Present Status and Future Considerations," J. Periodontol. 48, 497 (1977)
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