U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Solid phase immunoassay using immunoreagents immobilized on inert synthetic resin surfaces

Patent 4778767 Issued on October 18, 1988. Estimated Expiration Date: Icon_subject October 18, 2005. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3843443

Unitized solid phase immunoassay kit and method
Patent #: 4017597
Issued on: 04/12/1977
Inventor: Reynolds

Glass support coated with synthetic polymer for bioprocess
Patent #: 4357142
Issued on: 11/02/1982
Inventor: Schall, Jr. ,   et al.

Immunoassay with solid phase having coating containing blood platelet substitute
Patent #: 4360358
Issued on: 11/23/1982
Inventor: Sharma

Immunoassay with article having support film and immunological counterpart of analyte
Patent #: 4444879
Issued on: 04/24/1984
Inventor: Foster ,   et al.

Polycycloalkylidene-polycycloalkanes, epidioxy derivatives thereof and method of preparation Patent #: 4705847
Issued on: 11/10/1987
Inventor: Hummelen ,   et al.

Inventors

Assignee

Application

No. 06/682373 filed on 12/17/1984

US Classes:

436/531, Carrier is synthetic resin427/2.13, Layer formed contains chemical reagent or chemically reacts with substrate (e.g., cell stain or fix, pH paper, immobilized antigen)435/180, Carrier is synthetic polymer435/7.92, Heterogeneous or solid phase assay system (e.g., ELISA, etc.)435/7.94, Sandwich assay436/534, Carrier is water suspendible particles436/823, IMMUNOGENIC CARRIER OR CARRIER PER SE436/824IMMUNOLOGICAL SEPARATION TECHNIQUES

Examiners

Primary: Nucker, Christine M.

Attorney, Agent or Firm

International Classes

G01N 33/544 (20060101)
G01N 33/545 (20060101)

Abstract

A solid phase immunoassay comprises the steps of(a) immobilizing an immunoreagent on the surface of a carrier comprised of an inert synthetic resin selected from the group consisting of polyimides and polyfluorinated synthetic resins,(b) contacting the immunoreagent with a complementary immunoreagent whereby an immunocomplex immobilized on said carrier is formed,(c) quantitating the immobilized immunocomplex.An element useful in conducting this solid phase immunoassay is prepared by a process of treating the surface of an article comprised of a synthetic polymer selected from the group consisting of polyimides and polyfluorinated synthetic resins to make it adsorptive of an immunoreagent which comprises the steps of(a) thoroughly rinsing the surface with a water-miscible organic solvent,(b) thoroughly rinsing the surface with water.

Other References

  • Von Klitzing et al., Chemical Abstracts, vol. 99 (Sept. 1983) #101950j
  • Boffa et al., Chemical Abstracts, vol. 86 (Jun. 1977) #195181r
  • Von Kutzing et al., Chemical Abstracts, vol. 99 (Nov. 1983) #154586b
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