U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Fluoride-containing Bioglass™ compositions

Patent 4775646 Issued on October 4, 1988. Estimated Expiration Date: Icon_subject September 10, 2006. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3922155

Biocompatible glass ceramic material
Patent #: 3981736
Issued on: 09/21/1976
Inventor: Broemer ,   et al.

Bioglass coated A1203 ceramics
Patent #: 4103002
Issued on: 07/25/1978
Inventor: Hench ,   et al.

Method of bonding a bioglass to metal
Patent #: 4159358
Issued on: 06/26/1979
Inventor: Hench ,   et al.

Bioglass coated metal substrate Patent #: 4234972
Issued on: 11/25/1980
Inventor: Hench ,   et al.

Inventors

Assignee

Application

No. 06/906619 filed on 09/10/1986

US Classes:

501/2, Devitrified glass-ceramics428/432, Next to metal or compound thereof501/1, CERAMIC COMPOSITIONS501/57, Fluorine606/76, Specialized coating or material623/23.61Bone composition

Examiners

Primary: Capella, Steven

Attorney, Agent or Firm

International Classes

C03C 4/00 (20060101)
C03C 3/076 (20060101)
C03C 3/097 (20060101)
A61K 6/06 (20060101)
A61K 6/02 (20060101)
A61L 27/00 (20060101)
A61L 27/32 (20060101)
A61L 27/12 (20060101)
A61F 2/00 (20060101)

Abstract

A fluoride-containing bioactive glass composition suitable for bulk implant prosthetic devices and coatings for prosthetic devices, the bioactive glass compositions selected from glass formulations containing, by mole 46.1% SiO2, 2.6% P2 O5, 26.9% CaO and 24.4% Na2 O and glass formulations containing, by mole, 52.1% SiO2, 23.8% CaO, 21.5% Na2 O, 2.6% P2 O5 wherein, respectively, 30 to 50 molar percent and 40 to 60 molar percent of the CaO is substituted with CaF2. These fluoride-containing bioactive glass materials demonstrate high resistance to demineralization in physiological fluids as well as extensive apatite formation which shows a predominance of crystalline apatite of mixed phase character.

Other References

  • Hench et al., J. Biomedical Material Res. Symposium, No. 4, pp. 25-42 (1973)
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