U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Intra-pocket drug delivery devices for treatment of periodontal diseases

Patent 4764377 Issued on August 16, 1988. Estimated Expiration Date: Icon_subject February 13, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

2991224

3386440

3388704

3674901

3700685

3754332

3849185

Buccal implant for administering solubilizable products
Patent #: 4020558
Issued on: 05/03/1977
Inventor: Cournut ,   et al.

Antimicrobial sutures
Patent #: 4024871
Issued on: 05/24/1977
Inventor: Stephenson

Long-acting articles for oral delivery and process
Patent #: 4039653
Issued on: 08/02/1977
Inventor: DeFoney ,   et al.

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Inventor

Assignee

Application

No. 07/015521 filed on 02/13/1987

US Classes:

424/435, Mouth424/443, Web, sheet or filament bases; compositions of bandages; or dressings with incorporated medicaments424/449, Transdermal or percutaneous433/80Having intra-oral dispensing means

Examiners

Primary: Page, Thurman K.
Assistant: Horne, Leon R.

Attorney, Agent or Firm

International Classes

A61K 9/00 (20060101)
A61K 6/00 (20060101)
A61C 19/06 (20060101)
A61C 19/00 (20060101)

Abstract

Therapeutic agent delivery devices and methods for using them in treatment of dental disease are disclosed. In the treatment of periodontal disease, a therapeutic agent such as tetracycline mixed in a polymeric matrix such as ethylene vinyl acetate copolymer is packed into the area to be treated and kept in place for a suitable time, during which the therapeutic agent diffuses out of the polymeric matrix, providing continuous therapy for the treatment site.

Other References

  • J M. Goodson et al, "Monolithic Tetracycline-Containing Fibers for Controlled Delivery to Periodontal Pockets", J. Periodontology, 54, pp. 575-579 (1983)
  • Exerpts from "The Polymer Handbook", 2nd Edition, J. Brandrup and E. H. Immergut, Editors, John Wiley & Sons (1975)
  • Computer printouts concerning patents referred to in, or citing, U.S. Pat. Nos. 4,024,871 by Stephenson and 3,849,185 by Shepherd
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