Patent References 2991224 3386440 3388704 3674901 3700685 3754332 3849185 Buccal implant for administering solubilizable products Antimicrobial sutures Long-acting articles for oral delivery and process InventorAssigneeApplicationNo. 07/015521 filed on 02/13/1987US Classes:424/435, Mouth424/443, Web, sheet or filament bases; compositions of bandages; or dressings with incorporated medicaments424/449, Transdermal or percutaneous433/80Having intra-oral dispensing meansExaminersPrimary: Page, Thurman K.Assistant: Horne, Leon R. Attorney, Agent or FirmInternational ClassesA61K 9/00 (20060101)A61K 6/00 (20060101) A61C 19/06 (20060101) A61C 19/00 (20060101) AbstractTherapeutic agent delivery devices and methods for using them in treatment of dental disease are disclosed. In the treatment of periodontal disease, a therapeutic agent such as tetracycline mixed in a polymeric matrix such as ethylene vinyl acetate copolymer is packed into the area to be treated and kept in place for a suitable time, during which the therapeutic agent diffuses out of the polymeric matrix, providing continuous therapy for the treatment site.Other References
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