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US Patent 4760157 - (2,2,-bis(aminomethyl)-1,3-propanediol-N,N')platinum complexes
US Patent Issued on July 26, 1988
Estimated Patent Expiration Date:
January 31, 2006Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
Estimated Patent Expiration Date:
January 31, 2006Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.AbstractNovel organic-platinum compounds selected from those of the formulae: ##STR1## wherein L and L' are selected from the group consisting of halide, nitrate, sulfate and a monobasic carboxylate such as acetate or hydroxy acetate or L and L' taken together are a dibasic carboxylate selected from the group consisting of ##STR2## oxalic acid, methylmalonic acid, succinic acid and tartronic acid, or L and L' taken together are a tribasic carboxylate selected from the group consisting of ##STR3## taken together is ascorbic acid and X is selected from the group consisting of halogen and hydroxy. | InventorsAssigneeApplicationNo. 06/825023 filed on 01/31/1986US Classes:556/137, Nitrogen bonded directly to the metal987/11Devoid of any platinum atom directly bonded to carbon (15/00N7B)ExaminersPrimary: Shaver, Paul F.Attorney, Agent or FirmUS Patent References4140707, Malonato platinum anti-tumor compoundsIssued on: 02/20/1979 Inventor: Cleare , et al.4410544, Platinum-diamine complexes, a method for the preparation of a medicine using such a platinum-diamine complex for the treatment of malignant tumor in mice Issued on: 10/18/1983 Inventor: Berg , et al.4431666, Platinum(IV)-diamine complexes, a process for the preparation thereof, a process for the preparation of a medicine using such a platinum(IV)-diamine complex for the treatment of malignant tumors in mice Issued on: 02/14/1984 Inventor: Bulten , et al.4500465, Solubilized platinum (II) complexes Issued on: 02/19/1985 Inventor: Amundsen , et al.4587331Platinum complexes of polyhydroxylated alkylamines and 2-polyhydroxylated alkyl-1,2-diaminoethanes Issued on: 05/06/1986 Inventor: Hlavka , et al. International ClassC07F 15/00 (20060101) |
