Patent ReferencesMalonato platinum anti-tumor compounds Platinum-diamine complexes, a method for the preparation of a medicine using such a platinum-diamine complex for the treatment of malignant tumor in mice Platinum(IV)-diamine complexes, a process for the preparation thereof, a process for the preparation of a medicine using such a platinum(IV)-diamine complex for the treatment of malignant tumors in mice Solubilized platinum (II) complexes Platinum complexes of polyhydroxylated alkylamines and 2-polyhydroxylated alkyl-1,2-diaminoethanes Patent #: 4587331 InventorsAssigneeApplicationNo. 06/825023 filed on 01/31/1986US Classes:556/137, Nitrogen bonded directly to the metal987/11Devoid of any platinum atom directly bonded to carbon (15/00N7B)ExaminersPrimary: Shaver, Paul F.Attorney, Agent or FirmInternational ClassC07F 15/00 (20060101)AbstractNovel organic-platinum compounds selected from those of the formulae: ##STR1## wherein L and L' are selected from the group consisting of halide, nitrate, sulfate and a monobasic carboxylate such as acetate or hydroxy acetate or L and L' taken together are a dibasic carboxylate selected from the group consisting of ##STR2## oxalic acid, methylmalonic acid, succinic acid and tartronic acid, or L and L' taken together are a tribasic carboxylate selected from the group consisting of ##STR3## taken together is ascorbic acid and X is selected from the group consisting of halogen and hydroxy. |
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