Patent ReferencesAntibiotic bonding of vascular prostheses and other implants Patent #: 4442133 InventorsAssigneeApplicationNo. 06/850848 filed on 04/11/1986US Classes:428/422, Addition polymer is perhalogenated427/2.24, Implantable permanent prosthesis (i.e., artificial body member) (e.g., pacemaker, lens, cornea, glaucoma shunt, heart valve, muscle, spinal disc, breast, internal organ)427/2.25, Liquid conveying (e.g., vascular, arterial, bile duct, urethra)427/2.26, For mineralized body part (e.g., bone, tooth, crown, hip)428/457, Of metal521/30, Chemically treated solid polymer606/107, Means for removing, inserting or aiding in the removal or insertion of eye lens material623/1.42, Drug delivery623/1.43AntithrombogenicExaminersPrimary: Kight, JohnAssistant: Moore, M. L. Attorney, Agent or FirmInternational ClassesA61K 9/127 (20060101)A61L 27/54 (20060101) A61L 27/00 (20060101) A61L 33/00 (20060101) AbstractThere is disclosed an improved prosthesis coated, respectively, with an ionic surfactant, an antibiotic and/or antithrombiotic agent and treated with an immobilizing ionic exchange compound, to remove un-antibiotic bound ionic surfactant. The drug may be encapsulated within phospholipid vesicles which are bound to the prosthesis.Other References
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