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Water soluble salts of an NSAID with meglumine/glucamine

Patent 4748174 Issued on May 31, 1988. Estimated Expiration Date: Icon_subject January 5, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Salts of-carnitine and alkanoyl L-carnitines and process for preparing same Patent #: 4602039
Issued on: 07/22/1986
Inventor: Cavazza

Inventor

Assignee

Application

No. 07/000363 filed on 01/05/1987

US Classes:

514/226.5, One of the cyclos is a 1,2-thiazine (e.g.,1,2-benzothiazines, etc.)514/352, Nitrogen attached directly to the six-membered hetero ring by nonionic bonding514/365, 1,3-thiazoles (including hydrogenated)514/407, Chalcogen or nitrogen bonded directly to the pyrazole ring by nonionic bonding514/411, Tricyclo ring system having the five-membered hetero ring as one of the cyclos514/427, Two double bonds between ring members of the five-membered hetero ring (e.g., pyrrole, etc.)514/428, Chalcogen bonded indirectly to the five-membered hetero ring by acyclic nonionic bonding514/448, C=O bonded directly to the hetero ring (X is chalcogen)514/555, Benzene ring in acid moiety544/49, Benzothiazines (including hydrogenated)546/310, Having -C(=X)-, wherein X is chalcogen, bonded directly to the six-membered hetero ring548/187, The chalcogen, X, is in a -C(=X)- group548/361.5, Chalcogen bonded directly to ring carbon of the diazole ring548/432, Pyrano(3,4-b)indoles or thiopyrano(3,4-b) indoles (including hydrogenated)548/444, Chalcogen or nitrogen attached indirectly to the tricyclo ring system by acyclic nonionic bonding548/562, Chalcogen attached indirectly to the five-membered hetero ring by acyclic nonionic bonding548/565, One double bond between ring members of the five-membered hetero ring (i.e., pyrrolines)549/72, Nitrogen or chalcogen attached indirectly to the hetero ring by nonionic bonding560/143, Salicylic acid or functional derivative562/428, Indenyl or hydrindenyl562/456, Halogen562/457, Plural rings with nitrogen bonded directly to at least one ring562/459, Aldehyde or ketone562/460, Two rings bonded directly to the same carbonyl562/465, Oxy562/466, Polycyclo ring system562/469, Rings bonded directly to each other562/492Rings bonded directly to each other

Examiners

Primary: Ford, John M.

Attorney, Agent or Firm

International Classes

C07C 57/30 (20060101)
C07C 57/00 (20060101)
C07C 59/00 (20060101)
C07C 59/64 (20060101)
C07C 59/88 (20060101)
C07C 65/00 (20060101)
C07C 59/68 (20060101)
C07C 65/10 (20060101)
C07C 59/84 (20060101)
C07C 65/105 (20060101)

Foreign Application Priority Data

1986-01-03 IT

Abstract

The water soluble acid addition salts of an NSAID, such as acetylsalicylic acid, fenbufen, diflunisal, piroxicam, naproxen, or the like, with either glucamine or meglumine (N-methylglucamine) are useful anti-inflammatory and analgesic drugs, well adopted for parenteral, oral, rectal or topical administration.

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