U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Topical composition

Patent 4748022 Issued on May 31, 1988. Estimated Expiration Date: Icon_subject December 9, 2006. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3892853

Inventor

Application

No. 06/939475 filed on 12/09/1986

US Classes:

424/539, Bee514/579, Nitrogen containing other than solely as a nitrogen in an inorganic ion of an addition salt, a nitro or a nitroso DOAI514/716, Nitrogen containing514/717, Benzene ring containing514/817, ANESTHETIC, TOPICAL514/818ANESTHETIC, LOCAL

Examiners

Primary: Brown, J. Travis
Assistant: Rollins, John W.

Attorney, Agent or Firm

International Classes

A61K 35/64 (20060101)
A61K 35/56 (20060101)

Abstract

A composition and method of use for the treatment of pain and inflammation associated with lesions of the skin or mucus membrane, such as herpes simplex, herpes labialis, herpes progenitalis, chickenpox lesions, herpes genitalis, sensitivity of gingival tissue due to procedures for etching teeth with HCl, swollen gums, cheilosis, oral traumatic injuries, aphthous ulcer, by applying to the lesion an effective amount of a topical composition comprising diphenhydramine HCl, lidocaine HCl, aloe vera gel, propolis and sufficient base to raise the pH to 8-9.

Other References

  • Handbook of Nonprescription Drugs, 6th ed 1979, pp. 342 and 419
  • B. Havsteen, Biochem. Pharm. vol. 32(7):1141-1148, 1983
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