Erodible matrix for sustained release bioactive composition
Patent 4744976 Issued on May 17, 1988. Estimated Expiration Date: 
October 14, 2006. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
October 14, 2006. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3336155 3634584 3641236 Growth promotant controlled release formulations and method of treatment Drug delivery devices comprising erodible polymer and erosion rate modifier Process for the preparation of tablets with retarded liberation of the active agent is predetermined Patent #: 4351825 InventorsAssigneeApplicationNo. 06/918294 filed on 10/14/1986US Classes:424/408, Capsule or pelleted or tablet424/418, Protein or derivative or polysaccharide or derivative424/493, Containing polysaccharides (e.g., sugars)424/502, Contains waxes, higher fatty acids, higher fatty alcohols428/379, Including metal or compound thereof (excluding glass, ceramic and asbestos)428/401, Physical dimension428/402.24Microcapsule with solid core (includes liposome)ExaminersPrimary: Foelak, MortonAssistant: Moore, M. L. Attorney, Agent or FirmInternational ClassA61K 9/20 (20060101)AbstractA sustained release composition for releasing a biologically active compound into an aqueous liquid environment comprises the biologically active compound dispersed in a bioerodible matrix, the matrix comprising a mixture of(a.) 5% to 99.5% by weight of a solid water-dispersible polyether diol having a molecular weight from about 1000 to about 20,000, and(b.) 95 to 0.5% by weight of an erosion rate modifier component comprising a combination of stearyl alcohol and stearic acid.Dosage forms comprising the erodible matrix are prepared by molding, particularly by injection molding. | |
