Patent ReferencesPreparation of 4-aza-17-substituted-5-androstan-3-ones useful as 5-reductase inhibitors 4-Aza-17ଲ-substituted-5-androstan-3-one-reductase inhibitors Bile acids Patent #: 4388241 Inventors
ApplicationNo. 06/825348 filed on 02/03/1986US Classes:514/228.2, Polycyclo ring system having the additional hetero ring as one of the cyclos514/232.8, Polycyclo ring system having the additional hetero ring as one of the cyclos514/253.02, Polycyclo ring system having the additional six-membered nitrogen hetero ring as one of the cyclos514/284, Tetracyclo ring system having the six-membered hetero ring as one of the cyclos544/125, The additional six-membered hetero ring is one of the cyclos in a polycyclo ring system544/361, The additional six-membered hetero ring is one of the cyclos in a polycyclo ring system544/60, Additional hetero ring containing546/77, The six-membered hetero ring shares ring members with one other cyclo only546/78, Plural chalcogens bonded directly to carbocyclic rings of the tetracyclo ring system (e.g., pyridoanthraquinones, etc.)552/552, Exactly one oxygen bonded directly to the cyclopentanohydrophenanthrene ring system (e.g., 3-hydroxycholanic acids, lithocholic acids, etc.)560/5, Hydrophenanthrene in acid moiety562/403Hydrophenanthrene nucleusExaminersPrimary: Daus, Donald G.Assistant: Rivers, Diana G. Attorney, Agent or FirmInternational ClassesC07J 73/00 (20060101)C07J 41/00 (20060101) Foreign Application Priority Data1985-03-07 GBAbstractThe present invention relates to new 4-aza-17ଲ-substituted 5-androstan-3-ones, to a process for their preparation, to pharmacological compostions containing them, and to the use of said compounds as inhibitors of androgen action by means of testosterone 5-reductase inhibition.Other References
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