U.S. patents available from 1976 to present.
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Thienylthiazole compounds

Patent 4720493 Issued on January 19, 1988. Estimated Expiration Date: Icon_subject November 20, 2005. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Aminothiazoles
Patent #: 4307106
Issued on: 12/22/1981
Inventor: Lombardino

2-Guanidino-4-heteroarylthiazoles
Patent #: 4374843
Issued on: 02/22/1983
Inventor: La Mattina ,   et al.

Antiulcer 2-guanidino-4-(2-substituted-amino-4-imidazolyl)thiazoles and process therefor
Patent #: 4435396
Issued on: 03/06/1984
Inventor: LaMattina ,   et al.

2-(N-substituted guanidino)-4-hetero-arylthiazole antiulcer agents Patent #: 4560690
Issued on: 12/24/1985
Inventor: Reiter

Inventors

Assignee

Application

No. 06/799989 filed on 11/20/1985

US Classes:

514/236.8, Ring chalcogen in the additional hetero ring (e.g., oxazole, etc.)514/254.02, The additional five-membered hetero ring also has chalcogen as a ring member514/326, The additional ring is a hetero ring514/370, Nitrogen bonded directly to ring carbon of the thiazole ring514/371, C=X bonded directly to the nitrogen which is bonded directly to the thiazole ring (X is chalcogen)544/133, The five-membered hetero ring has at least sulfur and nitrogen as ring hetero atoms544/333, Additional hetero ring which is unsaturated544/367, Ring chalcogen in the five-membered hetero ring546/209, Ring sulfur or ring oxygen in the additional hetero ring546/270.7, Nitrogen attached directly to the 1,3-thiazole ring by nonionic bonding548/193, Chalcogen attached indirectly to the thiazole ring by nonionic bonding548/194, The chalcogen, X, is in a -C(=X)- group548/195The -C(=X)- group is bonded directly to the nitrogen

Examiners

Primary: Gerstl, Robert

Attorney, Agent or Firm

International Classes

C07D 417/00 (20060101)
C07D 417/04 (20060101)
C07D 333/38 (20060101)
C07D 333/22 (20060101)
C07D 417/14 (20060101)
C07D 333/00 (20060101)

Foreign Application Priority Data

1984-11-22 WO

Abstract

Thienylthiazole compounds of the formula: ##STR1## and pharmaceutically acceptable acid addition salts thereof, wherein: R is amino, guanidino, alkylamino, alkenylamino, unsubstituted or optionally substituted phenylamino or acylamino;A is amino, alkylamino, cyclic amino, alkanoylamino, a group of the formula: ##STR2## wherein each symbol is as defined in claim 1; Z is hydrogen or halogen; andm is 0 or 1 to 4,are useful in the treatment of peptic ulcer, acute or chronic gastritis, acute damage of gastric mucous membrane, dimentia and anxiety.

Other References

  • Chemical Abstracts, 100:122768k, 1984
  • Derwent CPI, 33756 K/14
  • Derwent CPI, 85-029014/05
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