U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Non-invasive blood flow measurements utilizing autoregressive analysis with averaged reflection coefficients

Patent 4719923 Issued on January 19, 1988. Estimated Expiration Date: Icon_subject May 6, 2005. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Method of and apparatus for measurement of blood flow using coherent light
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Issued on: 08/29/1978
Inventor: Stern ,   et al.

Duplex ultrasonic imaging system with repetitive excitation of common transducer in doppler modality
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Inventor: Papadofrangakis ,   et al.

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Patent #: 4324258
Issued on: 04/13/1982
Inventor: Huebscher ,   et al.

Noninvasive measurement of blood flow rate utilizing ultrasound
Patent #: 4327739
Issued on: 05/04/1982
Inventor: Chmiel ,   et al.

Ultrasonic imaging with volume flow measuring method and apparatus
Patent #: 4476874
Issued on: 10/16/1984
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Issued on: 09/24/1985
Inventor: Barnes ,   et al.

Inventors

Application

No. 06/730487 filed on 05/06/1985

US Classes:

600/454, Blood flow studies600/531Measuring metabolic rate by breath test

Examiners

Primary: Kamm, William E.
Assistant: Jaworski, Francis J.

Attorney, Agent or Firm

International Class

A61B 8/06 (20060101)

Abstract

A system for non-invasively determining the amount of blood flow within an internal patient blood vessel by performing an autoregressive analysis of Doppler shifted acoustical signals resulting from the reflection of ultrasonic signals due to blood cell movement by averaging the reflection coefficients and residual energy levels resulting from the autoregressive analysis over a number of cardiac cycles. The reflection coefficients result from a linear predictive code analysis, and the term "reflection coefficients" is not used in the customary manner as defined for ultrasonic flow analysis of blood as defining a level of reflected acoustic energy. Each cardiac cycle is determined by an analysis of the patient's electrocardiogram signals, and the resulting cardiac cycles are divided into a predefined number of time segments or channels. An autoregressive analysis is then performed on each individual channel to determine the reflection coefficients and the residual energy level for each channel. The reflection coefficients and residual energy level for each particular channel are then averaged over all the cardiac cycles to obtain an averaged reflection coefficient and averaged residual energy level for each combined channel. The power spectrum for each combined channel is then calculated from the averaged reflection coefficients and averaged residual energy level and displayed on a channel-by-channel basis utilizing different colors to represent the different power levels. The utilization of different colors greatly enhances the usability of the display by medical personnel making diagnostic decisions regarding the amount of blood flow.

Other References

  • "Computer Based Pattern Recognition of Carotid Artery Doppler Signals for Disease Classification: Prospective Validation", Y. E. Langlois, et al., Ultrasound in Med. & Biol., 1984, vol. 10, No. 5, pp. 581-595
  • "Analysis and Automatic Classification of Breath Sounds", A. Cohen, et al., IEEE Transactions on Biomedical Engineering, Sep., 1984, vol. BME-31, No. 9, pp. 585-590
  • "Flow Velocity Patterns in the Carotid Bifurcations of Young, Presumed Normal Subjects", D. J. Phillips, et al., Ultrasound in Med. & Biol., 1983, vol. 9, No. 1, pp. 39-49
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