Patent References 3201389 3337529 InventorsApplicationNo. 06/879215 filed on 06/27/1986US Classes:536/27.7, Chalcogen, halogen, or benzene bonded directly to carbon of the purine ring system (e.g., isoguanosine, 2-fluoroadenosine, etc.)536/26.7, The N-hetero ring is part of a bicyclic ring system536/27.21The five-membered N-hetero ring is 1,3-diazole, which may be hydrogenated (e.g., 6-chloropurine nucleoside, nebularin, etc.)ExaminersPrimary: Brown, J. TravisAssistant: Crane, L. Eric Attorney, Agent or FirmInternational ClassesC07H 19/20 (20060101)C07H 19/00 (20060101) AbstractNucleotide and nucleoside compounds are provided, namely 2-halo-2'-deoxyadenosine 5'-phosphate compounds (I) especially as the monosodium and disodium salt, and 2-iodo-2'-deoxyadenosine (II); as well as a method for their production, pharmaceutical compositions comprising the compounds, and methods of treatment using the compounds in dosage form. The compounds of the invention have pharmacological properties and are useful antimicrobial agents, antiviral agents, and antileukemic agents. ##STR1##Other References
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