Bioadhesive extruded film for intra-oral drug delivery and process
Patent 4713243 Issued on December 15, 1987. Estimated Expiration Date: 
June 16, 2006. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
June 16, 2006. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesSlow-releasing medical preparation to be administered by adhering to a wet mucous surface Sugar-coated tablet containing fat-soluble pharmaceutical material Mucous membrane-adhering film preparation and process for its preparation Patent #: 4517173 InventorsApplicationNo. 06/874904 filed on 06/16/1986US Classes:424/676, Sodium containing424/435, Mouth424/449Transdermal or percutaneousExaminersPrimary: Kulkosky, Peter F.International ClassA61K 9/00 (20060101)AbstractA bioadhesive extruded single or multi-layered thin film, especially useful in intra-oral controlled-releasing delivery, having a water soluble or swellable polymer matrix bioadhesive layer which can adhere to a wet mucous surface and which bioadhesive layer consists essentially of 40-95% by weight of a hydroxypropyl cellulose, 5-60% of a homopolymer of ethylene oxide, 0-10% of a water-insoluble polymer such as ethyl cellulose, propyl cellulose, polyethylene and polypropylene, and 2-10% of a plasticizer, said film having incorporated therein a medicament, e.g., anesthetics, analgesics, anticaries agents, anti-inflammatories, antihistamines, antibiotics, antibacterials, fungistats, etc. | |
