Soft steroids having anti-inflammatory activity
Patent 4710495 Issued on December 1, 1987. Estimated Expiration Date: 
April 8, 2005. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
April 8, 2005. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3558675 3856828 Pharmaceutical compositions of 6,9-difluoro-androst-4-ene-17ଲ-carboxylates and derivatives thereof Thio etianic acid derivatives Patent #: 4263289 InventorAssigneeApplicationNo. 06/721282 filed on 04/08/1985US Classes:514/174, -O-C-O- is part of a hetero ring (e.g., acetonide, etc.)514/179, Modified C-ring (except methyl in 13-position) (e.g., double bond containing, substituted, etc.)514/180, 9-position substituted540/36, Nitrogen attached directly or indirectly to the cyclopentanohydrophenanthrene ring system by nonionic bonding540/38, Chalcogen bonded directly at the 11-position of the cyclopentanohydrophenanthrene ring system552/528, The carbon is double bonded directly at the 16-position552/610Acyclic carbon bonded directly at the 17 beta-position of the cyclopentanohydrophenanthrene ring system (e.g., etiocholanic acids, 17 cyanoetiocholanes, 17-aldehydrostanes, etc.)ExaminersPrimary: Schenkman, LeonardAssistant: Lipovsky, Joseph A. Attorney, Agent or FirmInternational ClassesC07J 31/00 (20060101)C07J 33/00 (20060101) C07J 43/00 (20060101) C07J 3/00 (20060101) AbstractNovel soft steroid anti-inflammatory agents, said agents being esters or thioesters of 17-alkoxy-11ଲ-hydroxyandrost-4-en-3-one-17ଲ-carboxylic acids, pharmaceutical compositions containing said agents, novel chemical intermediates useful in the preparation of said agents and methods of administering same to mammals in the treatment of inflammation. Preferred compounds are the haloalkyl esters of 17-alkoxy-11ଲ-hydroxyandrost-4-en-3-one-17ଲ-carboxylic acids. |
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