InventorAssigneeApplicationNo. 06/830717 filed on 05/20/1986US Classes:514/253.04, Bicyclo ring having the additional six-membered nitrogen hetero ring as one of the cyclos514/277, Hetero ring is six-membered consisting of one nitrogen and five carbon atoms514/282, One of the five cyclos is five-membered and includes ring chalcogen (e.g., codeine, morphine, etc.)514/419, C=X bonded directly or indirectly by an acyclic carbon or carbon chain to ring carbon of the five-membered hetero ring (e.g., tryptophan, etc.) (X is chalcogen)514/479With an additional active ingredientExaminersPrimary: Friedman, Stanley J.Attorney, Agent or FirmInternational ClassA61K 31/495 (20060101)AbstractCompositions are disclosed for controlling pain, depression, and sedation. The compositions comprise a serotonin precursor such as L-tryptophan or L-5-hydroxytryptophan in combination with a serotonin-specific reuptake inhibitor such as trazodone. In a preferred embodiment, the compositions are coadministered with a narcotic, the composition substantially potentiating the analgesic effect of the narcotic.Other References
Field of SearchHetero ring is six-membered consisting of one nitrogen and five carbon atomsOne of the five cyclos is five-membered and includes ring chalcogen (e.g., codeine, morphine, etc.) C=X bonded directly or indirectly by an acyclic carbon or carbon chain to ring carbon of the five-membered hetero ring (e.g., tryptophan, etc.) (X is chalcogen) Ascorbic acid or derivative (e.g., vitamin C, etc.) | |