Patent ReferencesChemically joined, phase separated self-cured hydrophilic thermoplastic graft copolymers and their preparation Water-insoluble hydrophilic copolymers Water absorptive composition Patent #: 4300820 InventorAssigneeApplicationNo. 06/606794 filed on 05/03/1984US Classes:424/486, Synthetic polymer514/772.5Heterocyclic monomerExaminersPrimary: Friedman, Stanley J.Attorney, Agent or FirmInternational ClassesA61K 9/20 (20060101)A61K 47/32 (20060101) C08L 39/06 (20060101) C08L 57/00 (20060101) C08L 39/00 (20060101) AbstractNovel hydrogel compositions, comprised of a blend of two thermoplastic uncrosslinked polymers, one of which is hydrophobic, and the other hydrophilic, and having a microphase separated morphology are described. These hydrogel compositions are useful as devices for controlling the release rate of bioactive agents, such as therapeutic drugs, antimicrobials, contraceptive agents, or the like, in a biological environment. Depending upon the chemical nature of the agent to be released, its rate of release can be controlled by appropriate selection of the polymeric components of the blend and their relative ratios.Other References
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