U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Method for delivering an active ingredient by controlled time release utilizing a novel delivery vehicle which can be prepared by a process utilizing the active ingredient as a porogen

Patent 4690825 Issued on September 1, 1987. Estimated Expiration Date: Icon_subject October 4, 2005. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3390050

3516941

3720534

3886084

Controlled release materials and method of use
Patent #: 3985298
Issued on: 10/12/1976
Inventor: Nichols

Process for production of spherical porous fillers for liquid chromatography by suspension polymerization of monovinyl and polyvinyl aromatic monomers in the presence of paraffin wax
Patent #: 3989649
Issued on: 11/02/1976
Inventor: Kaiho ,   et al.

Method of manufacturing spherical polymer particles from polymer solutions
Patent #: 4110529
Issued on: 08/29/1978
Inventor: Stoy

Highly adsorptive macroporous polymers
Patent #: 4307201
Issued on: 12/22/1981
Inventor: Won ,   et al.

Process for producing controlled porosity microcapsules
Patent #: 4322311
Issued on: 03/30/1982
Inventor: Lim ,   et al.

Encapsulation of labile biological material
Patent #: 4324683
Issued on: 04/13/1982
Inventor: Lim ,   et al.

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Inventor

Assignee

Application

No. 06/784382 filed on 10/04/1985

US Classes:

424/501, Contains solid synthetic resin424/502, Contains waxes, higher fatty acids, higher fatty alcohols514/963, Microcapsule-sustained or differential release514/965, Discrete particles in supporting matrix521/63Cellular product-forming process wherein the removable material is present or is produced in situ during the solid polymer formation step

Examiners

Primary: Griffin, Ronald W.

Attorney, Agent or Firm

International Classes

A61K 9/16 (20060101)
C08J 9/28 (20060101)
C08J 9/00 (20060101)

Abstract

Delivery vehicles comprised of a polymeric bead having a network of pores with an active ingredient held within the network are provided for use in a method to provide controlled release of the active ingredient. The network of pores is substantially non-collapsible upon removal of the active ingredient and the delivery vehicles are polymerized by a process in which the active ingredient also comprises the porogen during formation of the network of pores.

Other References

  • Brunauer, S. Emmet, P.H., & Teller, E., J. Am. Chem. Soc., 60, 309-16 (1938)
  • Barrett, E.P., Joyner, L. G. & Helenda, P. O., J. Am. Chem. Soc., 73, 373-80 (1951)
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