Patent References 2798838 3907983 InventorAssigneeApplicationNo. 06/735046 filed on 05/17/1985US Classes:424/469, Discrete particles in supporting matrix264/109, FORMING ARTICLES BY UNITING RANDOMLY ASSOCIATED PARTICLES264/123, Autogenously or by activation of dry coated particles424/471, Plural concentric cores427/2.19Retarded or controlled-release layer produced (e.g., enteric)ExaminersPrimary: Scluenberg, SamAttorney, Agent or FirmInternational ClassesA61K 9/20 (20060101)A61J 3/10 (20060101) A61K 9/50 (20060101) A61M 31/00 (20060101) AbstractThis invention relates to new dosage units of medicinal agents for oral administration in the form of tablets which provide a controlled rate of release of the medicament in the gastrointestinal tract. More particularly, the invention relates to dense compressed tablets comprising mainly sustained release coated pellets processed such that the tablets disintegrate rapidly in aqueous and gastric fluids at body temperature, releasing the medicinal agent contained therein gradually over a relatively long period of time. | |