Identification of Neisseria gonorrhoeae
Immunometric assays using monoclonal antibodies
Isolation of principal outer membrane protein and antigen of Chlamydia trachomatis
Method for the detection and/or determination of a polyvalent antigen using at least two different monoclonal antibodies Patent #: 4471058
ApplicationNo. 06/590211 filed on 03/16/1984
US Classes:435/7.35, Salmonella435/7.32, Bacteria or actinomycetales435/7.36, Sexually transmitted disease (e.g., chlamydia, syphilis, gonorrhea, etc.)435/7.37, Escherichia coli435/7.9, Assay in which an enzyme present is a label435/7.94, Sandwich assay435/810, PACKAGED DEVICE OR KIT435/948, Using viruses or cell lines435/975, KIT436/548, Monoclonal antibody436/807, APPARATUS INCLUDED IN PROCESS CLAIM (E.G., PHYSICAL SUPPORT STRUCTURES, ETC.)530/388.4, Binds bacterium or similar microorganism or component or product thereof (e.g., Stretococcus, Legionella, Mycoplasma, bacterium-associated antigen, exotoxin, etc.)530/389.5, Binds bacterium or similar microorganism or component or product thereof (e.g., Pseudomonas, Chlamydia, Clostridium, bacterium-associated antigen, etc.)530/808, MATERIALS AND PRODUCTS RELATED TO GENETIC ENGINEERING OR HYBRID OR FUSED CELL TECHNOLOGY, E.G., HYBRIDOMA, MONOCLONAL PRODUCTS, ETC.530/809Fused cells, e.g., hybridoma, etc.
ExaminersPrimary: Kepplinger, Esther M.
Attorney, Agent or Firm
International ClassesC12Q 1/04 (20060101)
G01N 33/569 (20060101)
G01N 33/577 (20060101)
Foreign Application Priority Data1983-12-12 CA
AbstractThe subject invention provides a means for the immunological detection of an entire class of microorganisms in clinical samples. The detection is accomplished by reaction of the clinical sample iwth a class-specific immunological reagent. This reagent is an antiserum either monoclonal or polyclonal in nature, and the detection is based upon reaction of the antiserum with an antigenic determinant which is shared among all members of the detectable class of microorganisms. The presence of the resulting immunological reaction product (e.g. the antigen-antibody complex) may be detected by well-known immunological detection-systems.