U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Stable prostaglandin E gels utilizing colloidal silicon dioxide as a gel-forming agent

Patent 4680312 Issued on July 14, 1987. Estimated Expiration Date: Icon_subject November 21, 2004. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3749800

3816393

3826823

3829579

3927197

Triacetin solutions of PGE-type compounds
Patent #: 3966962
Issued on: 06/29/1976
Inventor: Yalkowsky

Triethyl citrate solutions of PGE-type compounds
Patent #: 4211793
Issued on: 07/08/1980
Inventor: Lodhi ,   et al.

3-Hydroxy and 3-oxo-prostaglandin analogues
Patent #: 4351846
Issued on: 09/28/1982
Inventor: Matsumoto ,   et al.

Trans-Ɗ2 -pge alkylsulphonyl amides Patent #: 4390548
Issued on: 06/28/1983
Inventor: Yamato ,   et al.

Inventor

Assignee

Application

No. 06/674357 filed on 11/21/1984

US Classes:

514/573, Cyclopentyl or cyclopentene (e.g., prostaglandins, etc.)514/944GEL

Examiners

Primary: Robinson, Douglas W.

Attorney, Agent or Firm

International Class

A61K 31/557 (20060101)

Foreign Application Priority Data

1982-03-22 GB

Abstract

The present invention provides an improved class of stable gels of prostaglandin E compounds prepared from solutions of prostaglandin E compounds in a pharmaceutically acceptable, stabilizing organic solvent, e.g., triacetin, gelled by the addition of colloidal silicon dioxide.

Other References

  • Calder, A. A., et al., "Ripening of a Cervix with Extra Amniotic Prostaglandin E2 in Viscous Gel Before Induction of Labor," Brit. J. OB/GYN, 84:264-268 (1977)
  • Eros, I., et al., "Applications of Colloidal Silicon Dioxide in Pharmaceutical Technology, II, Gysgyszereszet 19(8), 290-5 (1975), Chem. Abstracts 83:18331q (1975)
  • M. Sherriff and R. P. Enever, "Rheological and Drug Release Properties of Oil Gels Containing Coloidal Silicon Dioxide," J. Pharm. Sci., 68(7), 842-845 (1979)
PatentsPlus Images
Enhanced PDF formats
loading...
PatentsPlus: add to cart
PatentsPlus: add to cartSearch-enhanced full patent PDF image
$9.95more info
PatentsPlus: add to cart
PatentsPlus: add to cartIntelligent turbocharged patent PDFs with marked up images
$18.95more info
 
Sign InRegister
Username  
Password   
forgot password?