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AbstractA novel formulation of piroxicam for dermatological administration is disclosed. Pharmaceutical compositions containing piroxicam, lower alkanols, water, carboxyvinyl polymer, polyhydric alcohols, alkanolamines and optionally film-forming agents are prepared, said compositions having a pH of from about 6.5 to about 9.0. The novel formulation is characterized by excellent applicability on the skin, skin-permeability and good stability. The novel formulation, which is in gel ointment form, is as effective as orally administered peroxicam and is well suited for topical administration through skin for the treatment of various types of inflammatory conditions.Other References
| InventorsApplicationNo. 06/896370 filed on 08/14/1986US Classes:514/224.2, Polycyclo ring system having the six-membered hetero ring as one of the cyclos (e.g., 1,3- and 1,4- benzothiazines, etc.)424/78.05Anti-inflammatory or anti-irritant (e.g., anti-arthritic, etc.)ExaminersPrimary: Friedman, Stanley J.Attorney, Agent or FirmUS Patent References3591584, 4434164Crystalline benzothiazine dioxide saltsIssued on: 02/28/1984 Inventor: Lombardino International ClassesA61K 9/70 (20060101)A61K 47/38 (20060101) A61K 47/10 (20060101) A61K 47/32 (20060101) A61K 47/18 (20060101) A61K 47/16 (20060101) A61K 31/54 (20060101) Foreign Application Priority Data1982-07-13 JP |