U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Treatment of chronic inflammatory disease with polyvalent immunoglobulins

Patent 4676982 Issued on June 30, 1987. Estimated Expiration Date: Icon_subject August 4, 2006. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Production of Protein A Patent #: 4617266
Issued on: 10/14/1986
Inventor: Fahnestock

Inventor

Assignee

Application

No. 06/892655 filed on 08/04/1986

US Classes:

424/177.1, Reduced antigenicity, reduced ability to bind complement, or reduced numbers of activated complement components (e.g., free from aggregated, denatured, fragmented, or polymerized immunoglobulins; free from proteolytic enzymes, etc.)424/130.1, IMMUNOGLOBULIN, ANTISERUM, ANTIBODY, OR ANTIBODY FRAGMENT, EXCEPT CONJUGATE OR COMPLEX OF THE SAME WITH NONIMMUNOGLOBULIN MATERIAL530/387.1, Immunoglobulin, antibody, or fragment thereof, other than immunoglobulin antibody, or fragment thereof that is conjugated or absorbed530/390.5, Removing, dissociating, or preventing the formation of aggregated, denatured, fragmented, or polymerized immunoglobulin or antibody; or preventing or reducing complement fixation or binding; or reducing antigenicity; or removing, inactivating, or inhibiting contaminating plasma proteins (e.g., proteolytic enzymes, etc.)530/868INVOLVING AUTOIMMUNITY, ALLERGY, IMMEDIATE HYPERSENSITIVITY, DELAYED HYPERSENSITIVITY, IMMUNOSUPPRESSION, OR IMMUNOTOLERANCE

Examiners

Primary: Schain, Howard E.

Attorney, Agent or Firm

International Classes

C07K 16/18 (20060101)
A61K 38/00 (20060101)

Foreign Application Priority Data

1985-08-07 GB

Abstract

Chronic inflammatory disease of the bowel, e.g. ulcerative colitis and Cr's disease, is treated by infusion of an intravenously injectable form of a polyvalent, intact immunoglobulin (IgG).

Other References

  • Acta Path. Microbiol. Scandinav. 75, 466-480 (1969), Forsgren et al
  • Journal of Immunology, 103, 467-473 (1969), Sjoquist et al
  • Journal of Immunology, 97, 822-827 (1966), Forsgren et al
  • Acta Path. Microbiol. Scandinav. 73, 400-406, (1968), Grov
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