Patent ReferencesProduction of Protein A Patent #: 4617266 InventorAssigneeApplicationNo. 06/892655 filed on 08/04/1986US Classes:424/177.1, Reduced antigenicity, reduced ability to bind complement, or reduced numbers of activated complement components (e.g., free from aggregated, denatured, fragmented, or polymerized immunoglobulins; free from proteolytic enzymes, etc.)424/130.1, IMMUNOGLOBULIN, ANTISERUM, ANTIBODY, OR ANTIBODY FRAGMENT, EXCEPT CONJUGATE OR COMPLEX OF THE SAME WITH NONIMMUNOGLOBULIN MATERIAL530/387.1, Immunoglobulin, antibody, or fragment thereof, other than immunoglobulin antibody, or fragment thereof that is conjugated or absorbed530/390.5, Removing, dissociating, or preventing the formation of aggregated, denatured, fragmented, or polymerized immunoglobulin or antibody; or preventing or reducing complement fixation or binding; or reducing antigenicity; or removing, inactivating, or inhibiting contaminating plasma proteins (e.g., proteolytic enzymes, etc.)530/868INVOLVING AUTOIMMUNITY, ALLERGY, IMMEDIATE HYPERSENSITIVITY, DELAYED HYPERSENSITIVITY, IMMUNOSUPPRESSION, OR IMMUNOTOLERANCEExaminersPrimary: Schain, Howard E.Attorney, Agent or FirmInternational ClassesC07K 16/18 (20060101)A61K 38/00 (20060101) Foreign Application Priority Data1985-08-07 GBAbstractChronic inflammatory disease of the bowel, e.g. ulcerative colitis and Cr's disease, is treated by infusion of an intravenously injectable form of a polyvalent, intact immunoglobulin (IgG).Other References
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