Pharmaceutical compositions containing hollow fine tubular drug delivery systems
May 3, 2005. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3458616 3512183 3854480 3875300 Self-monitored device for releasing agent at functional rate Microsealed pharmaceutical delivery device Apparatus for controlling the release of a drug Controlled release of medicaments using polymers from glycolic acid Broadcast dissemination of trace quantities of biologically active chemicals Method for permanently and uniformly incorporating an additive into an undrawn fiber InventorsAssigneeApplicationNo. 06/730064 filed on 05/03/1985US Classes:424/443, Web, sheet or filament bases; compositions of bandages; or dressings with incorporated medicaments514/965Discrete particles in supporting matrixExaminersPrimary: Griffin, Ronald W.International ClassesA61K 9/00 (20060101)A61K 9/70 (20060101) AbstractPharmaceutical compositions are provided which contain hollow fine tube drug delivery systems. The compositions comprise a pharmaceutically suitable carrier, preferably in the form of a capsule, tablet, suspension, or suppository, and at least one drug delivery system which consists essentially of (1) a polymeric tube having a membrane outer sheath and a hollow core, and (2) at least one drug compound contained within the core, said system contained in the composition in an amount sufficient to deliver a therapeutic amount of the drug contained therein at a predetermined rate over a predetermined period of time. By varying the polymer, the permeability of the outer sheath, the drug, the drug concentration in the hollow core of the tube, the tube diameter, the tube length, the tube core diameter, and the sealing of the tube ends, a wide variety of drug therapeutic amounts, rates and dosing times can be achieved.Other References
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