"I hate what they've done to my child...I would never let my own children watch it. "
Vladimir Zworykin, television pioneer ; Talking about an invention in which he played a critical role.
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AbstractThe present invention relates to novel 5-substituted pyrazolo[4,3-d]pyrimidine-7-one compounds, and compositions, methods of use and processes to make therefor. The novel compounds are useful in the treatment of cardiovascular disorders, such as heart failure or cardiac insufficiency. The novel compounds bind adenosine receptors and selectively inhibit phosphodiesterase.Other References
| InventorApplicationNo. 06/720437 filed on 04/05/1985US Classes:514/234.2, Three or more ring hetero atoms in the bicyclo ring system514/232.5, Polycyclo ring system having the additional hetero ring as one of the cyclos514/262.1, Exactly four ring nitrogens in the bicyclo ring system544/118, Four or more ring nitrogens in the bicyclo ring system544/262The other cyclo in the bicyclo ring system is five-memberedField of Search544/262The other cyclo in the bicyclo ring system is five-memberedExaminersPrimary: Rosen, SamAssistant: Benson, Robert Attorney, Agent or FirmUS Patent References3165520, 39391611,3-Dimethyl- 1H-pyrazolo(4,3-D) pyrimidine-7 (6H)-onesIssued on: 02/17/1976 Inventor: Ratajczyk , et al. International ClassesC07D 487/00 (20060101)C07D 487/04 (20060101) |