Disc-like sustained release formulation
September 3, 2005. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 2851648 3113076 3146169 Microporous drug delivery device Osmotic dispenser with gas generating means Ocular therapeutic system manufactured from copolymer Systems for the controlled release of macromolecules Constant-rate eluting tablet and method of producing same Device with integrated operations for controlling release of agent System for delivering agent at zero order rate with emerging agent below saturation InventorAssigneeApplicationNo. 06/771816 filed on 09/03/1985US Classes:424/467, Printed, embossed, grooved, or perforated424/473, With porous, perforated, apertured, or sieved layer (e.g., dialyzing layer, microporous layer, etc.)424/486Synthetic polymerExaminersPrimary: Rose, Shep K.Attorney, Agent or FirmInternational ClassA61K 9/20 (20060101)AbstractA device for the release of a diffusible solid in a fluid medium which comprises a disc which comprises a substantially uniform mixture of said diffusible solid and a polymer which is insoluble in and impermeable to said fluid medium and impermeable to said diffusible solid. The surfaces of said disc are coated with a polymer which is insoluble in and impermeable to said fluid medium and impermeable to said diffusible solid, with the exception of one or more apertures which extend through the disc and expose a portion of the mixture of diffusible solid and polymer to the fluid medium when the device is immersed therein. The aperture or apertures are placed in said disc such that as said fluid medium enters the disc through said aperture or apertures, the ratio of surfce area of diffusible solid exposed to the fluid medium to the length of the path through which the exposed solid must diffuse to exit the disc remains substantially constant. | |
