U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Apparatus and method for the detection and classification of articles using flow cytometry techniques

Patent 4661913 Issued on April 28, 1987. Estimated Expiration Date: Icon_subject September 11, 2004. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Apparatus for measuring cytological properties
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Issued on: 09/30/1980
Inventor: Gohde

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Automated method for cell volume determination
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Patent #: 4352558
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Patent #: 4468742
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Method and apparatus for the classification of piece goods which are in a state of motion
Patent #: 4514816
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Particle sorter with neutralized collection wells and method of using same
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Issued on: 09/03/1985
Inventor: Hoffman

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Inventors

Application

No. 06/649449 filed on 09/11/1984

US Classes:

702/19, Biological or biochemical356/442, With light detector382/133, Cell analysis, classification, or counting422/73, With coagulometer for agglutination, clotting, or prothrombin, or for particle (e.g., cell, etc.) counting, or volume or characteristics determination422/82.05, Measuring optical property by using ultraviolet, infrared, or visible light422/82.08, Fluorescence422/82.09, Absorbance or transmittance436/63BIOLOGICAL CELLULAR MATERIAL TESTED

Examiners

Primary: Krass, Errol A.
Assistant: Teska, Kevin J.

Attorney, Agent or Firm

International Classes

G01N 15/14 (20060101)
G06K 9/00 (20060101)

Abstract

This invention concerns a flow apparatus and method for the detection of particles in a sample. Particles are moved, substantially one at a time, in a fluid flow stream. An incident beam of illumination is provided so as to be directed at the particles in the flow stream. Data associated with each moving particle as it passes through the beam of illumination is detected. A class of particles is established, these particles having common characteristics based on the data detected from such class of particles. The data is then stored. Such stored data is compared to data detected from sample particles of an unknown class. A determination is then made that particles from the unknown class belong to the established class as a result of matching respective data.

Other References

  • Scientific American 234(3):108, 1976, "Fluorescence-Activated Cell Sorting", Herzenberg et al, pp. 108-117
  • Adv. Computers 12:285-414, 1972, "Parametric & Nonparametric Recognition by Computer . . . ", Prewitt, pp. 285-414
  • Anal. Quant. Cytol. (1979, 1980, 1981), "Numerical Evaluation of Cytologic Data", parts I-VIII, Bartels
  • Flow Cytometry & Sorting, "Cytometric Data Processing", Sharpless, Pub John Wiley & Sons, 1979, pp. 359-379
  • J. Histochem. Cytochem.; 27:560, 1978; "Visualization of Multi-Dimensional Spectra in Flow Cytometry", Stohr et al
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