Patent References 3789832 Method of obtaining internal information of a measuring target from the out-side by the application of a nuclear magnetic resonance phenomenon Phenethylamine antigenic conjugates, their preparation, antibodies, and use Method of obtaining information of a specified or target area of a living body near its skin surface by the application of a nuclear magnetic resonance phenomenon Imaging systems Imaging systems Nuclear magnetic resonance systems Patent #: 4449097 InventorsApplicationNo. 06/680058 filed on 12/10/1984US Classes:424/9.33, Nitroxide or nitroxide containing436/173, NUCLEAR MAGNETIC RESONANCE, ELECTRON SPIN RESONANCE OR OTHER SPIN EFFECTS OR MASS SPECTROMETRY436/803, STABE FREE RADICALS (E.G., SPIN IMMUNOASSAY, ETC.)436/806, ELECTRICAL PROPERTY OR MAGNETIC PROPERTY540/512, Chalcogen attached indirectly to nitrogen of the hetero ring by acyclic nonionic bonding540/514, Nitrogen in the 1-position substituent of the bicyclo ring system600/420Using detectable material placed in bodyExaminersPrimary: Nucker, Christine M.Assistant: Wieder, Stephen C. Attorney, Agent or FirmInternational ClassesA61K 49/20 (20060101)A61K 49/06 (20060101) AbstractAn improved imaging technique involving nuclear magnetic resonance. Known drug or neurotransmitter receptor ligands are covalently bound to magnetic resonance image enhancing spin label compounds, such as sterically hindered free radical nitroxide compounds, with the resulting adduct being administered to a patient, and thereafter when the ligand is bound to specific receptor sites in the soft tissue such as the brain, regional tissue area is assessed with nuclear magnetic resonance, allowing diagnostic discrimination.Other References
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