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US Patent 4650675 - Oligonucleotide conjugates

US Patent Issued on March 17, 1987
Estimated Patent Expiration Date: Icon_subject March 17, 2004Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
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Abstract

Conjugate composed of an oligonucleotide covalently bonded to a carrier.

Other References

  • Yves Borel et al. (1973), American Association for the Advancement of Science, 182 76-78
  • Papalian et al. (1980) J. Clin Invest., 65 469-477
  • Borel et al. (1980) Proc. Natl. Acad. Sci. 77 1593-6
  • Golan et al. (1971) The Journal of Experimental Medicine, 134 1046-1061
  • Molin et al. (1978) The Journal of Histochemistry and Cytochemistry 26 1053-6
  • Ellis et al. (1976) Progress in Medicinal Chemistry, 13 272-301
  • Hopwood, David, Histochemical Journal, 7 (1975) 267-276

Inventors

Assignee

Application

No. 06/524298 filed on 08/18/1983

US Classes:

424/179.1, Conjugated via claimed linking group, bond, chelating agent, or coupling agent (e.g., conjugated to proteinaceous toxin via claimed linking group, bond, coupling agent, etc.)424/178.1, CONJUGATE OR COMPLEX OF MONOCLONAL OR POLYCLONAL ANTIBODY, IMMUNOGLOBULIN, OR FRAGMENT THEREOF WITH NONIMMUNOGLOBULIN MATERIAL530/391.7, Conjugated to a cytotoxic agent, drug, or other biologically-active substance530/391.9, Conjugated via a specifically-identified linking group, coupling agent, or conjugation agent530/868INVOLVING AUTOIMMUNITY, ALLERGY, IMMEDIATE HYPERSENSITIVITY, DELAYED HYPERSENSITIVITY, IMMUNOSUPPRESSION, OR IMMUNOTOLERANCE

Examiners

Primary: Hazel, Blondel

US Patent References

3725545, 3821193, 4372883, Process for the production of vaccine
Issued on: 02/08/1983
Inventor: Matuhashi ,   et al.
4388306, Pharmaceutical composition comprising modified polyriboinosinic-polyribocytidylic acid, for induction of interferon in primates
Issued on: 06/14/1983
Inventor: Field ,   et al.
4400375, Tobramycin-double stranded RNA complex suitable for inducing interferon
Issued on: 08/23/1983
Inventor: Douthart ,   et al.
4460575, Vaccinal complex containing a specific antigen and vaccine containing it
Issued on: 07/17/1984
Inventor: d'Hinterland ,   et al.
4472301Propranolol immunogen and antibodies
Issued on: 09/18/1984
Inventor: Buckler ,   et al.

International Class

A61K 47/48 (20060101)

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