Hybrid cell line for producing monoclonal antibody to a human early thymocyte antigens, antibody, and methods
Patent 4624925 Issued on November 25, 1986. Estimated Expiration Date: 
November 25, 2003. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
November 25, 2003. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesMonoclonal antibody to a human early thymocyte antigen and methods for preparing same Anti-human T-lymphocyte monoclonal antibody Monoclonal antibodies specific for the human transferrin receptor glycoprotein Patent #: 4434156 InventorsAssigneeApplicationNo. 06/432458 filed on 10/04/1982US Classes:435/343.2, Binds a T-lymphocytic cell or component or product thereof (e.g., T-cell, thymocyte, T-lineage bone marrow cell, T-lymphoblastoid cell, T-lineage acute lymphoblastic leukemia cell, T-lymphocytic cell surface antigen, etc.)424/154.1, T lymphocytic cell (e.g., T cell, thymocyte, etc.)435/70.21, Producing monoclonal antibody435/948Using viruses or cell linesExaminersPrimary: Wiseman, Thomas G.Assistant: Tarcza, John E. Attorney, Agent or FirmInternational ClassesC07K 16/28 (20060101)C07K 16/18 (20060101) G01N 33/569 (20060101) A61K 38/00 (20060101) AbstractHybrid cell line for production of monoclonal antibody to an antigen found on approximately 10% of normal human thymocytes. The hybrid is formed by fusing splenocytes from immunized CAF1 mice with P3X63Ag8U1 myeloma cells. Diagnostic and therapeutic uses of the monoclonal antibody are also disclosed.Other References
Field of SearchUsing viruses or cell lines |
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