Patent References 3089824 Composite core coated microparticles and process of preparing same Patent #: 4568559 InventorsAssigneeApplicationNo. 06/803733 filed on 12/02/1985US Classes:428/402.24, Microcapsule with solid core (includes liposome)424/497, Containing solid synthetic polymers427/2.16, Retarded or controlled-release layer produced (e.g., enteric)427/213Fluidized bed utilizedExaminersPrimary: Kittle, John E.Assistant: Shah, Mukund J. Attorney, Agent or FirmInternational ClassesA61K 9/16 (20060101)A61K 9/50 (20060101) AbstractA process for preparing coated microparticles, which process comprises preparing a solvent solution of an active ingredient to be encapsulated and a film-forming polymer, removing the solvent to provide a dry, composite, uniform admixture of the active ingredient and the polymer material, reducing the composite admixture to a defined smaller particle size distribution, coating the reduced composite core particles in a fluidized bed, with a uniform defined wall thickness of the same or substantially the same film-forming polymer material to provide composite core coated microparticles. | |