Patent References 2463962 2497057 2985562 2999293 3401216 3480185 3773922 3903255 Effervescent stannous fluoride tablet Patent #: 4267164 InventorApplicationNo. 06/643980 filed on 08/20/1984US Classes:424/44, Gas produced in situ by chemical reaction252/183.16, Contains carbonate or bicarbonate252/363.5, SOLIDS WITH SOLUTION OR DISPERSION AIDS514/163, With carboxylic acid, ester or metal salt thereof514/474, Ascorbic acid or derivative (e.g., vitamin C, etc.)514/629, R is hydrogen or a lower saturated alkyl of less than seven carbons514/960, SIGNIFICANT, TABLET FORMULATION (E.G., DESIGNATED EXCIPIENT, DISINTEGRANT, GLYDENT OR LUBRICANT, ETC.)514/961, Binder therefor516/19The compound contains -C(=O)OH group or salt thereofExaminersPrimary: Lovering, Richard D.Attorney, Agent or FirmInternational ClassesA61K 9/46 (20060101)B01J 2/16 (20060101) Foreign Application Priority Data1982-12-21 FRAbstractThe invention relates to a process for manufacturing effervescent tablets consisting in the steps of careful humidifying of the acid+base mixture, pre-drying and final drying and granulating.It has been found that these operations can be performed in a single apparatus, either integrally in fluid bed, or with vacuum-drying. | |