U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Antidepressant 1,2,4-triazolone compounds

Patent 4613600 Issued on September 23, 1986. Estimated Expiration Date: Icon_subject September 30, 2003. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3381009

3857845

Phenoxyethyl-1,2,4,-triazol-3-one antidepressants Patent #: 4338317
Issued on: 07/06/1982
Inventor: Temple, Jr. ,   et al.

Inventors

Assignee

Application

No. 06/538027 filed on 09/30/1983

US Classes:

514/254.05, Plural nitrogens in the additional five-membered hetero ring544/366Five-membered hetero ring having two or more ring hetero atoms of which at least one is nitrogen

Examiners

Primary: Lesmes, George F.
Assistant: Gibson, S. A.

Attorney, Agent or Firm

International Classes

C07D 249/00 (20060101)
C07D 249/12 (20060101)

Abstract

2-[3-[4-(3-Halophenyl)-1-piperazinyl]propyl]-5-(1-hydroxyethyl)-2,4-dihydro -[4-phenoxyalkyl-3H-1,2,4-triazol-3-ones and closely related compounds are psychotropic agents having promise as antidepressants by virtue of their receptor site binding affinity profiles and animal pharmacology.

Other References

  • La Selva, et al., Riv. Neuropsichiat. Sci. Affini., 25/2, 57-68 (1979)
  • Silvestrini, et al., International Journal of Neuropharmacology, 7, 587-599 (1968)
  • Fabre, et al., Current Therapeutic Research, 25, 827-834 (1979)
  • Temple, Jr., et al., U.S. Ser. No. 06/509,266 filed 6/29/83
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