Patent ReferencesAryloxyphenylpropylamines in treating depression Patent #: 4018895 InventorAssigneeApplicationNo. 06/732478 filed on 05/09/1985US Classes:564/348, Hydroxy, bonded directly to carbon, or ether oxygen is attached directly or indirectly to the chain by acyclic nonionic bonding with no amino nitrogen between the hydroxy or attached ether oxygen and the aryl ring or ring system (H of -OH may be replaced by a substituted or unsubstituted ammonium ion or a Group IA or IIA light metal)560/142, Nitrogen or sulfur in phenolic moiety560/252, Polyoxy alcohol moiety564/171, Plural rings in substituent Q564/347The ether oxygen is bonded directly to the aryl ring or ring systemExaminersPrimary: Warren, Charles F.Assistant: Sopp, John A. Attorney, Agent or FirmInternational ClassesC07C 233/00 (20060101)C07C 233/12 (20060101) AbstractThis invention provides a group of hydroxycycloalkanephenoxyethylamine antidepressant derivatives of the following structural formula: ##STR1## in which R1 is hydrogen or alkyl of 1 to 6 carbon atoms;R2 is alkyl of 1 to 6 carbon atoms;R3 and R4 are independently hydrogen, hydroxyl, alkyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms, alkanoyloxy of 2 to 7 carbon atoms, halo or trifluoromethyl;R5 is hydrogen, alkyl of 1 to 6 carbon atoms or alkanoyl of 2 to 7 carbon atoms;and n is one of the integers 0, 1, 2 or 3;or a pharmaceutically acceptable salt thereof.Other References
Field of SearchHydroxy, bonded directly to carbon, or ether oxygen is attached directly or indirectly to the chain by acyclic nonionic bonding with no amino nitrogen between the hydroxy or attached ether oxygen and the aryl ring or ring system (H of -OH may be replaced by a substituted or unsubstituted ammonium ion or a Group IA or IIA light metal)Plural rings in substituent Q |
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