U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Method for stimulating recovery from ischemia employing ribose and adenine

Patent 4605644 Issued on August 12, 1986. Estimated Expiration Date: Icon_subject February 7, 2005. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Inventor

Assignee

Application

No. 06/699037 filed on 02/07/1985

US Classes:

514/45, Purines (including hydrogenated) (e.g., adenine, guanine, etc.)514/23Carbohydrate (i.e., saccharide radical containing) DOAI

Examiners

Primary: Brown, Johnnie R.
Assistant: Peselev, Elli

Attorney, Agent or Firm

International Class

A61K 31/70 (20060101)

Abstract

The perfusion of ischemic tissue with dilute physiological salt solutions containing adenine and ribose reduces the period required for tissue function recovery and for the restoration of tissue of ATP levels.

Other References

  • H G. Zimmer et al., Pflugers Arch., 376, 223 (1978)
  • H. I. Seifart et al., Basic Res. Cardiol., 75, 57 (1980)
  • J. E. Folker, et al., J. Thorac, Cardiovasc. Surg., 80, 506 (1980)
  • H. G. Zimmer, Science, 250, 81 (1983)
  • M. K. Pasque, et al., in J. Thorac, Cardiovasc. Surg., 83, 390 (1982)
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