U.S. patents available from 1976 to present.
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Method and apparatus for rapid NMR imaging using multi-dimensional reconstruction techniques

Patent 4599565 Issued on July 8, 1986. Estimated Expiration Date: Icon_subject July 19, 2003. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Gyromagnetic resonance fourier transform zeugmatography
Patent #: 4070611
Issued on: 01/24/1978
Inventor: Ernst

Nuclear magnetic resonance apparatus and methods
Patent #: 4115730
Issued on: 09/19/1978
Inventor: Mansfield

Method and apparatus for rapid NMR imaging of nuclear densities within an object
Patent #: 4318043
Issued on: 03/02/1982
Inventor: Crooks ,   et al.

Imaging systems Patent #: 4322684
Issued on: 03/30/1982
Inventor: Hounsfield

Inventors

Assignee

Application

No. 06/515117 filed on 07/19/1983

US Classes:

324/309To obtain localized resonance within a sample

Examiners

Primary: Levy, Stuart S.
Assistant: Raevis, Robert

Attorney, Agent or Firm

International Classes

G01N 24/08 (20060101)
G01N 24/00 (20060101)

Abstract

An imaging NMR scanner generates multi-dimensional NMR spin echo responses from selected sub-volumes of an object. 90° and 180° r.f. nutation pulses are used together with a variable amplitude gradient between these nutation pulses to phase encode a second dimension in the spin echo response which is already phase-encoded in a first dimension by use of a magnetic gradient during signal readout. Two-dimensional Fourier transforms or multiple angle projection reconstruction processes are then used to generate an array of pixel value data signals representing a visual image of the point-by-point spatial distribution of nutated nuclei within the object. Image artifacts potentially caused by relatively moving elements of the object are avoided by selecting the spin echo generating sub-volumes to avoid the moving elements. High resolution images of sub-volumes of interest can be obtained by selection of a sub-volume of interest in conjunction with these reconstruction techniques. Solutions for possible aliasing artifacts are also presented as are three-dimensional reconstruction techniques using NMR spin echo responses from such selected sub-volumes.

Other References

  • J Phip. E: Sci. Instrum, vol. 13, (1980), pp. 697-707, "Automation and Control in High Power Pulsed NMR" by Geiger et al
  • J. Mag. Nes. 29 (1978) 355-73 (particularly 363-7), "Biological and Medical Imaging by NMR" by Mansfield et al
  • Phip. Rev. 94(4) (1/5/54) 630-8 (see FIG. 6), "Effects of Diffusion on Free Precession in Nuclear Magnetic Resonance Experiments" by Carr et al
  • J. Mag. Res. 33 83-106 (1979), "Sensitivity and Performance Time in NMR Imaging" by Brunner et al
  • Letters to the Edition, May 12, 1980, "Spin Wrap NMR Imaging and Applications to Human Whole-Body Imaging" by Edelstein et al
  • Abstract for 22nd Experimental NMR Conference Apr. 5-9, 1981, "In Vivo Comparison of Line Scan and Two Dimensional FT Imaging" by Crooks
  • AJR: 137, Nov. 1981, pp. 895-901, "Magnetic Resonance Properties of Hydrogen: Imaging the Posterior Fossa" by Young et al
  • J. Couput, Assist, Tomograph., vol. 6, No. 1982, "Initial Clinical Evaluation of a Whole Body Nuclear Magnetic Resonance (NMR) Tomograph" by Young et al
  • Rev. Sci. Instrum., 53(a), Sep. 1982, "NMR Imaging Techniques and Applications: Review" by Bottomley
  • Radiology, vol. 143, No. 1, pp. 169-174, Apr. 1982, "Nuclear Magnetic Resonance Whole Body Imager Operating at 3.5 K Gauss" by Crooks, et al
  • "NMR Tomograph" by Bradley, 1982
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