Transcutaneous application of nicotine
Patent 4597961 Issued on July 1, 1986. Estimated Expiration Date: 
January 23, 2005. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
January 23, 2005. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 1775998 3598122 3598123 3731683 3742951 Novel drug delivery device Slow-releasing medical preparation to be administered by adhering to a wet mucous surface Patent #: 4292299 InventorApplicationNo. 06/694047 filed on 01/23/1985US Classes:424/448, Pressure sensitive adhesive means424/449, Transdermal or percutaneous514/314, Additional hetero ring attached directly or indirectly to the quinoline ring system by nonionic bonding514/813TobaccoExaminersPrimary: Griffin, Ronald W.Attorney, Agent or FirmInternational ClassesA61K 9/70 (20060101)A61K 31/465 (20060101) AbstractPercutaneous administration of nicotine in a dose approximating the dose delivered by a variety of nicotine-containing products, such as cigarettes, cigars, snuff and chewing tobacco, is carried out using an occlusive pad. The nicotine is delivered so as to mimic the pharmacological effects of nicotine provided by the conventional use of tobacco, and a therapeutic function is achieved by reducing or eliminating the need for the tobacco product. A suitable transdermal application pad comprises a reservoir for liquid nicotine base to be affixed to the skin in a variety of places. Due to the high lipid solubility and resultant high skin permeability of nicotine, vehicles or solvents are not generally needed to enhance dermal absorption.Other References
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