U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Screening method for red cell abnormality

Patent 4596464 Issued on June 24, 1986. Estimated Expiration Date: Icon_subject December 2, 2003. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3686486

Process for automatic counting and measurement of particles
Patent #: 4021117
Issued on: 05/03/1977
Inventor: Gohde ,   et al.

Hematocrit measurement in an automatic hematology analyzer
Patent #: 4086631
Issued on: 04/25/1978
Inventor: Vick

Apparatus for counting and classifying particles
Patent #: 4110043
Issued on: 08/29/1978
Inventor: Eisert

Technique for simultaneous particle size and velocity measurement
Patent #: 4251733
Issued on: 02/17/1981
Inventor: Hirleman, Jr.

Pulse edge measurement for determining particle dimensional characteristics
Patent #: 4263508
Issued on: 04/21/1981
Inventor: Leary ,   et al.

Method and apparatus for measuring mean cell volume of red blood cells Patent #: 4453266
Issued on: 06/05/1984
Inventor: Bacus

Inventors

Assignee

Application

No. 06/557689 filed on 12/02/1983

US Classes:

356/336, By particle light scattering356/39, BLOOD ANALYSIS377/11, Including particle size determination variations702/21, Cell count or shape or size analysis (e.g., blood cell)702/26By particle count

Examiners

Primary: McGraw, Vincent P.
Assistant: Thompson, III, Robert D. V.

Attorney, Agent or Firm

International Classes

G01N 15/14 (20060101)
G01N 15/00 (20060101)

Abstract

Red cell samples are passed through a zone of focused illumination, and a scatter vs. time pulse is obtained for each. Each pulse is analyzed for pulse width, pulse area, and pulse shape. These parameters are respectively collected, and three coefficients of variation are obtained for each such collection. In addition to these three abnormality factors, the mean of the pulse shape collection constitutes a fourth. The four are respectively subject to statistical criteria, and are combined in predetermined fashion for a single red cell morphology index.

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