Patent ReferencesSodium chromoglycate inhalation medicament Composition for treating airway disease Patent #: 4161516 InventorsAssigneeApplicationNo. 06/606542 filed on 05/03/1984US Classes:514/456, Bicyclo ring system having the hetero ring as one of the cyclos (e.g., chromones, etc.)514/826, ASTHMA514/951POWDERS, GRANULES OR PARTICLES OF SPECIFIED MESH OR PARTICLE SIZEExaminersPrimary: Schenkman, LeonardAttorney, Agent or FirmInternational ClassA61K 9/16 (20060101)Foreign Application Priority Data1981-07-24 GBAbstractThere is described a finely divided inhalation drug, e.g. sodium cromoglycate, comprising a therapeutically effective proportion of individual particles capable of penetrating deep into the lung, characterized in that a bulk of the particles which is both unagglomerated and unmixed with a coarse carrier, is sufficiently free flowing to be filled into capsules on an automatic filling machine and to empty from an opened capsule in an inhalation device. A number of the individual drug particles have a spherical, collapsed spherical or ring doughnut shape.There is also described a method of making the fine particles and pharmaceutical formulations containing them.Other References
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