Treatment of negative symptoms of schizophrenia
Patent 4588721 Issued on May 13, 1986. Estimated Expiration Date: 
November 26, 2004. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
November 26, 2004. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3907820 6-Phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepines Benzodiazepine derivatives Patent #: 4116956 InventorAssigneeApplicationNo. 06/674616 filed on 11/26/1984US Classes:514/220Tricyclo ring system having the seven-membered hetero ring as one of the cyclosExaminersPrimary: Friedman, Stanley J.Attorney, Agent or FirmInternational ClassA61K 31/55 (20060101)AbstractTherapeutic process for treating the negative symptoms of schizophrenia in humans comprising the systematic administration of a compound of the formula ##STR1## X is a member selected from the group consisting of --H, --CH3, and --CH2 --O--R;wherein R is hydrogen, alkyl of from 1 to 3 carbon atoms, inclusive, ##STR2## wherein n is 0 to 16, inclusive, and m is 1 to 16 inclusive; Y is hydrogen or, provided when Z is hydrogen and X is CH3, hydroxy;Z is hydrogen or, provided when Y is hydrogen and X is --CH3, chloro;including the N-oxides and pharmacologically acceptable acid addition salts thereof in combination with a pharmaceutical carrier.Other References
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